The lock-and-key analogy for the enzymes applies to the specificity of enzymes_______. Naim 23:16 AP Biology Chapter 8 The lock-and-key analogy for the enzymes applies to the specificity of enzymes_______. a.) binding to their substrates b.) interacting with ions c.) interacting with water d.) as they form their tertiary and quaternary structure Answer: A Learn More : Share this Share on FacebookTweet on TwitterPlus on Google+