In the presence of oxygen, the three-carbon compound pyruvate can be catabolized in the citric acid cycle. First, however, the pyruvate 1) loses a carbon, which is given off as a molecule of CO2. 2) is oxidized to form a two-carbon compound called acetate, and 3) is bonded to coenzyme A.
Which of the following intermediary metabolites enters the citric acid cycle and is formed, in part, by the removal of a carbon (CO2) from one molecule of pyruvate?
A. Lactate
B. Glyceraldehyde-3-phosphate
C. Oxaloacetate
D. Acetyl CoA
E. Citrate
Answer: D