During cellular respiration, acetyl CoA accumulates in which location? Naim 12:00 AP Biology Chapter 9 During cellular respiration, acetyl CoA accumulates in which location? A. Cytosol B. Mitochondrial outer membrane C. Mitochondrial inner membrane D. Mitochondrial intermembrane space E. Mitochondrial matrix Answer: E Learn More : Share this Share on FacebookTweet on TwitterPlus on Google+