Where do the microtubules of the spindle originate during mitosis in both plant and animal cells? Naim 23:20 The Cell Cycle Where do the microtubules of the spindle originate during mitosis in both plant and animal cells? A) centromere B) centrosome C) centriole D) chromatid E) kinetochore Answer: B Learn More : Share this Share on FacebookTweet on TwitterPlus on Google+