The osmoregulatory/excretory system of an earthworm is based on the operation of Naim 00:38 AP Biology Chapter 32 The osmoregulatory/excretory system of an earthworm is based on the operation of A) metanephridia. B) ananephredia. C) protonephridia. D) nephrons. E) Malpighian tubules. Answer: A Learn More : Share this Share on FacebookTweet on TwitterPlus on Google+